TNF and Alzheimer disease: It has also been noted that the levels of inflammatory cytokines (tumour necrosis factor-alpha (TNFα), interleukin 1 (IL1), interleukin 6 (IL6), interleukin 8 (IL8), interleukin 10 (IL10), etc.)differ in AD patients compared with cognitively healthy people both in peripheral blood and cerebrospinal fluid (CSF) [2,3].