Our findings for CYP19A1 concurred with previous studies that evaluated the mRNA expression in the granulosa of large follicles in comparison to follicular cysts, confirming that cows diagnosed with COF, independent of the number of days postpartum for diagnosis, have a lower mRNA expression of CYP19A1 (37, 39). The gene discussed is CYP19A1; the disease is Follicular Cyst.