SDC1 and Carcinoma, Lewis Lung: In a recent study, the authors found that SCGB3A2, worked as a chaperone, directly interacted with syndecan-1 (SDC1) to facilitate the delivery of lipopolysaccharide (LPS) into the cytosol and stimulated pyroptosis in Lewis lung carcinoma (LLC) cells via up-regulating the caspase-11/NLRP3 pathway.