In addition, a lncRNA termed Lymph Node Metastasis Associated Transcript 1 (LNMAT1), upregulated in lymph node-positive bladder cancer and associated with lymph node metastasis and prognosis, could epigenetically activate CCL2 expression and recruit macrophages into the tumor, which promoted lymphangiogenesis via VEGF-C secretion. This evidence concerns the gene DUXAP9 and metastatic malignant neoplasm in the lymph nodes.