NRP2 and colorectal carcinoma: Neuropilin-2 (NRP2), another important regulator of lymphangiogenesis, was directly suppressed by miR-486-5p in colorectal carcinoma cells, leading to the reduction of peritumoral lymphatic microvessels in vivo, and thus demonstrating the suppressor role of miR-486-5p in colorectal carcinoma (105).