Since intraperitoneal injection of bexarotene decreased expression of CCL22, CXCL5, and CXCL10 mRNA in EL4 mouse T-cell lymphoma, we hypothesized that serum levels of CCL22, CXCL5, or CXCL10 might be associated with response in CTCL patients treated with bexarotene. Here, CCL22 is linked to T-cell non-Hodgkin lymphoma.