CXCL5 and neoplasm: Although both CXCL5 and CXCL10 are important for immunosuppression in the tumor microenvironment by recruiting polymorphonuclear MDSCs, neutrophils, Tregs, and effector T cells in solid tumor such as melanoma, renal cell carcinoma, esophageal carcinoma, and pancreatic cancer (23–27), bexarotene did not affect serum levels of CXCL5 and CXCL10 in the present study.