ITGB5 and glioblastoma: We then analyzed ITGB5 expression in different GBM subtypes using CGGA and TCGA datasets and found that ITGB5 was more closely associated with the mesenchymal phenotype (Figures 2E,F;, Figure S2A), suggesting that it could serve as a diagnostic marker for this subtype (Figures 2G,H; Figure S2B).