Contrastingly, SSRI antidepressants metabolized by CYP2C19 are significantly associated with the following ADRs: electrocardiogram QT prolonged (n = 351) OR = 0.18 (95% CI [0.13–0.24], p = 2.88E-28), small for dates baby (n = 306) OR = 0.19 (95% CI [0.14–0.26], p = 2.52E-24), and hyponatraemia (n = 808) OR = 0.31 (95% CI [0.26–0.37], p = 2.61E-37). This evidence concerns the gene CYP2C19 and Hyponatremia.