The top three ADRs associated with SSRIs metabolized by CYP2D6 were found to be: nightmare (n = 983) reporting OR = 4.37 (95% CI [3.67–5.20], p = 8.67E-62), panic attack (n = 1,243) OR = 2.43 (95% CI [2.11–2.79], p = 2.94E-36), and hyperhidrosis (n = 1,476) OR = 2.34 (95% CI [2.05–2.66], p = 5.33E-38). Here, CYP2D6 is linked to Hyperhidrosis.