TNFSF10 and cancer: Aside from the conventional therapies, the selective induction of apoptosis in target cancer cells with pro-apoptotic cytokines, such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) (Merino et al., 2007) seems promising, as this strategy exhibited low toxicity to non-cancerous cells, including brain cells, in clinical trials (Stuckey and Shah, 2013).