This is the case of the amplified oncogenes AKT1 (Hyman et al., 2017) and WT1 (Bergmann et al., 1997), and of the receptor tyrosine kinase gene FLT4, which regulates lymphangiogenesis and tumor metastasization to lymphatic vessels (Lee et al., 2016). This evidence concerns the gene WT1 and neoplasm.