IFNG and tuberculosis: To get additional evidence on the role of IL17F in tuberculosis, we wondered whether individuals carrying the C variant of the rs763780 SNP would display a weaker immune response against Mtb. Thus, PBMCs from HD and TB, discriminated in C carriers, or non-C carriers, were stimulated with Mtb-Ag, and we evaluated IL17F, IFNG, and IL17A production, proliferation index and SLAM expression (Figure 3).