More importantly, the concordance of putative enhancers in both schizophrenia-associated loci with genes across the entire GRB (Fig. 3c), including SNX19, supports the idea that variants rs10791097 (found just downstream of, and originally thought to be a bystander locus to SNX19 [42]) and rs75059851 share some mechanistic aspects in the aetiology of the disease, and calls for testing for effects of their interaction despite the large genomic distance between them. This evidence concerns the gene SNX19 and schizophrenia.