Meanwhile, the recognized target genes of miR-101, such as c-Fos, ZEB1 and Mcl-1, known to promote tumor growth (Gonzales-Aloy et al., 2019; Pan et al., 2015; Stavropoulou et al., 2016), were significantly decreased in AML cells transduced with sh-SNHG1 (Fig. 4B). Here, MCL1 is linked to acute myeloid leukemia.