CD40LG and Hashimoto thyroiditis: Higher level of anti-β2GPI Abs (IgM) (p ≤ 0.0001) were detected in the amniotic fluid (AF) of pregnant women belonging to RPL group, smoking group and autoimmune hypothyroidism (ahT) group compared with women with physiological pregnancies (control group) (Figs. 1, 2 and 3).