Ukinc et al. [7] found that the fPSA is present with equilibrium with PSA in serum and also found the diagnostic value of fPSA reached 70.5% sensitivity and 82% specificity for PCOS, more importantly, the author also recommends that PSA could be used for diagnosis of PCOS with high sensitivity, specificity, and diagnostic accuracy. Here, KLK3 is linked to polycystic ovary syndrome.