Though strong evidence does not yet exist linking SLC1A5 to cardiovascular mechanisms, its CpGs have shown associations with diabetes, blood pressure, and mortality [50–52], and we note that its companion amino acid transporter, SLC7A5, is known to regulate metabolic and inflammatory reprogramming of monocytes in response to stimulation by lipopolysaccharide (LPS). The gene discussed is SLC7A5; the disease is diabetes mellitus.