In subgroup analysis of IBS subtype, IL23R rs11465804 increased the risk for IBS-C both in AM (G vs. T, OR = 1.346, 95% CI: 1.025–1.767, P = 0.032) and DM (TG + GG vs. TT, OR = 1.338, 95% CI: 1.005–1.781, P = 0.046) (Fig. 3d). The gene discussed is IL23R; the disease is irritable bowel syndrome.