IL6 and irritable bowel syndrome: This finding was interesting because there was no association of the G allele with IBS in the Caucasian subgroup, but in Caucasian subgroups with diagnostic Rome III criteria (Fig. 3c), the IL6 rs1800795 G allele significantly increased the risk for IBS (OR = 2.057, 95% CI: 1.313–3.225, P = 0.002).