Forward selection [likelihood ratio (LR)] in binary logistic regression analysis revealed that malignant disease (OR 2.73, 95%CI 1.10–6.78), ADL category (OR 0.82, 95%CI 0.75–0.89), and serum albumin (OR 0.86, 95%CI 0.78–0.95) were independent risk factors for in-hospital mortality among nonagenarian patients with infectious diseases (Table 3). This evidence concerns the gene ALB and infectious disease.