RAD50 and central nervous system disorder: Other interesting genes, such as Rad50 (BGIBMGA005449), which is associated with DNA repair functions [44–46] and the histidine triad protein gene (BGIBMGA011899), which plays roles in transcription, signal transduction and many peripheral and central nervous system diseases [47] are also shown different mRNA transcript level and DNA methylated level upon BmNPV infection (Table 1).