INS and type 2 diabetes mellitus: As reported in Table 1, the subjects in the NGT group were younger (p < 0.0001 versus IFG/IGT and T2DM) and showed a significantly better profile for metabolic parameters, such as FPG (p < 0.0001 versus IFG/IGT and T2DM), 2-h post load plasma glucose (p < 0.0001 versus IFG/IGT and T2DM), insulin levels (p < 0.001 versus IFG/IGT and p < 0.0001 versus T2DM), HbA1c% (p < 0.001 versus IFG/IGT and p < 0.0001 versus T2DM), HOMA-IR and Matsuda Index (each with p < 0.0001 versus IFG/IGT and T2DM), after adjusting for age, sex, and BMI.