Rountree, et al. [97] developed an exosome-based anti-prostate cancer vaccine—MVA-BN-PRO—that contained two chimeric proteins derived from tumor-associated antigens, prostate-specific antigen (PSA), and prostatic acid phosphatase (PAP) fused to the C1C2 domain of lactadherin, targeting them specifically to the exosome. This evidence concerns the gene KLK3 and Familial prostate cancer.