Another possible mechanism is via the PI3K/AKT/mTOR pathway, which is known as a potential predictor of the distinct invasive and migratory capacities of human ovarian cancer cells [37], but we failed to detect phosphorylation of AKT by ALDH1A2 overexpression in ovarian cancer cells (data not shown). The gene discussed is ALDH1A2; the disease is ovarian carcinoma.