We previously reported that survivin, an anti-apoptotic protein, is involved in osimertinib resistance in glioma stem cells (GSCs), the CSCs of glioblastoma [43], and in NSCLC cells [44], and also that aripiprazole and brexpiprazole, antipsychotic drugs, reduce the expression of survivin and chemosensitize NSCLC and pancreatic cancer cells to gemcitabine [45,46]. This evidence concerns the gene BIRC5 and central nervous system cancer.