Exogenous modulation of miR-7 levels and CRHR2 activation in various CRC cell lines had opposing effects on YY1 and Fas expressions and cell sensitivity to CH11-mediated apoptosis, thus suggesting specificity of CRHR2/Ucn2 inhibitory action on YY1, via miR-7 [207]. Here, UCN2 is linked to colorectal carcinoma.