The serum 6-miRNA signature combined with f(Hb) values showed a Sn of 81% and a Sp of 78% for CRC, and a Sn of 81% and Sp of 69% for AA, these values were better than using f(Hb) alone (Sn = 81%, Sp = 73% for CRC and Sn = 81%, Sp = 35% for AA, respectively). Here, GSTM1 is linked to colorectal carcinoma.