As such, these different dynamics of AKT activation [42,50,51,52,53] could result in the observed discrepancies of the downstream signaling and explain the differences from our results, where musclin was not induced by MyrAKT in vitro in four day-differentiated immortalized C2C12 myotubes at any time tested (24, 48 and 72 h post-infection). The gene discussed is AKT1; the disease is infection.