F8 and hemarthrosis: The bleeds in the AG were all minor and not related to PA: One ankle haemarthrosis, provoked by ankle sprain while working the same day the patient received the prophylactic treatment; one spontaneous hip haemarthrosis, one day after the last FVIII infusion (mean steps/day: 13,220; steps on the day of bleeding: 12,925); and spontaneous bleeding in the knee in a patient who received daily prophylactic treatment (mean steps/day: 12,347; steps on the day of bleeding: 12,249 steps).