PARP1 and cancer: Since PARP inhibitor monotherapy strategies are effective in cancers with homologous recombination repair defects and are relatively well-tolerated by patients, they can be considered for the treatment of a wider range of cancers, both in combined therapies, due to the well-established fact that these drugs sensitize cells to DNA-damaging chemotherapy and radiation therapy, or as an alternative to taxanes and a supplement to anthracyclines [36,37,38].