The combination of plasma miR-125a-5p, let-7e (downregulated), and CEA increased diagnostic accuracy (AUC: 0.66 for miR-125a-5p + CEA, 1.00 for let-7e + CEA, and 1.00 for miR-125a-5p + let-7e + CEA vs. 0.534 for CEA) for early-stage NSCLC vs. healthy controls [101]. Here, CEACAM5 is linked to non-small cell lung carcinoma.