To evaluate the expression of PATZ1 in pediatric gliomas, we initially analyzed public databases by using the R2: Genomic Analysis and Visualization platform (http://r2.amc.nl), screening a microarray dataset of pediatric brain samples (GSE50161), including eight normal cerebral cortex tissues obtained from autopsy or epilepsy surgery and 49 glial tumors (15 pLGG and 34 pHGG) [22] that we used in our study. The gene discussed is PATZ1; the disease is central nervous system cancer.