PATZ1 and neoplasm: To further investigate PATZ1 expression in pediatric glial tumors and correlate it with clinicopathological features, we collected tumor samples, including 24 pLGG and 28 pHGG from 52 young patients aged from 6 months to 16 years, and analyzed PATZ1 expression by immunohistochemistry (IHC) using a polyclonal antibody able to recognize all PATZ1 isoforms [19].