Additionally, the concentration of dopamine showed a significant positive correlation with VMAT2 expression in the putamen of DLB brains (Fig. 3c, rs = 0.667, p = 0.050), further proving in all likelihood that dopamine accumulates in the cytosol by means of dopamine transporter followed by sequestration into the synaptic storage vesicles by VMAT2. This evidence concerns the gene SLC6A3 and Lewy body dementia.