CAPN3 encodes a calcium modulated nonlysosomal protease predominantly expressed in skeletal muscle.10 Limb girdle muscle dystrophy 2A (LGMD2A), due to CAPN3 mutations is one of the most frequent muscular dystrophies, however, its presence in the Roma population has not been reported before. This evidence concerns the gene CAPN3 and autosomal recessive limb-girdle muscular dystrophy type 2A.