IGF1 and hypopituitarism: Sleep parameters worsened in 5 patients (20.8%; 3 male and 2 female) between T0 and T1, although there was no increase in IGF-1 levels in these patients (4 out of 5 had a normal or decreased IGF-1 level relative to T0), they did not develop pituitary hormonal deficiencies, and BMI was stable or declined in all but 1 female patient, who had a significantly higher BMI at T1 compared to T0.