No differences have been found between PAPS and secondary APS patients (SAPS) in terms of age (p = 0.190), gender (p = 0.21), cardiovascular risk factors [including arterial hypertension (p = 0.281), hyperlipidemia (p = 0.670), and smoking habit (p = 0.290)], C-reactive protein values (p = 0.540) and HDL cholesterol levels (p = 0.721), and aPL profile (all p > 0.050). The gene discussed is CRP; the disease is Hypertension.