We were specifically interested in evaluating the performance of a previously established adult seven-marker serum protein biosignature (CRP, transthyretin, IFN-γ, CFH, Apo-AI, IP-10, and SAA) (28) as a tool for the diagnosis of childhood TBM, and to also evaluate the potential of other host biomarkers. Here, CXCL10 is linked to meningeal tuberculosis.