Liao et al. reported a nine-gene prognostic model (ARHGAP30, HCLS1, CD96, FAM78A, ARHGAP15, SLA2, CD247, GVINP1, and IL16) using weighted gene co-expression network analysis that may predict overall survival of pancreatic cancer patients after pancreaticoduodenectomy (24).These articles explored prognosis-related genes from different perspectives to establish prognostic signatures. The gene discussed is HCLS1; the disease is pancreatic neoplasm.