The cutoff points for LAVI and NT-proBNP indicating an increased risk of ESUS were lower in our study than those accepted in the standards for the diagnosis of heart failure (125 pg/mL compared to 99 pg/mL in our study) and LAVI (34 mL/m2 compared to 24 mL/m2 in our study). This evidence concerns the gene NPPB and heart failure.