In addition, although the OS of MGMT methylated GBM patients was significantly longer than that of MGMT unmethylated GBM patients (Supplementary Figure 1), we noticed that the OS of MGMT unmethylated GBM patients in the low-risk group was similar to that of MGMT methylated GBM patients in both the training and validation datasets (Figures 3C, D). Here, MGMT is linked to glioblastoma.