DUX4 and hematologic disorder: Based on the literature, DUX4 could act as an oncogene in various sarcomas and hematological malignancies (Dib et al., 2019), while we could not find information in the literature revealing a putative oncogenic role for MTRNR2L2. These TET3-controlled genes are worth further investigation to establish their causal effect in mammary tumorigenesis in future work.