In BB muscles, except for BIN1 (in both DM1 and DM2 patients), DMD1 (in DM2 patients), and SERCA1 (in DM1 patients), a statistically significant alteration of alternative splicing of the genes examined was present in DM1 and DM2 compared to CTR muscles (data not shown). This evidence concerns the gene BIN1 and myotonic dystrophy type 1.