However, the stromal expression domains of Sdc1 (p = 1,1033 × 10–6), HPSE1 (p = 0,0023), EXT1 (p = 1,2849 × 10–7), NDST1 (p = 0,000105), and CD45 (p = 0,003747) showed significant difference between controls and periodontitis group. This evidence concerns the gene HPSE and periodontitis.