FGF10 and malignant colon neoplasm: The FGF-10 gene upregulation was observed in 69 % of all tumors located in colon, suggesting the importance of FGF-10 as a risk factor for colon cancer, as the results of three large phase III randomized clinical trials have reported that the tumor location is an important factor for overall survival of patients who experienced curative surgery for colon cancer (Aoyama et al., 2017[4]).