In order to select the most promising ligand for clinical translation, [64Cu]DOTA-R01, [64Cu]DOTA-R01-MR, and [64Cu]DOTA-R01-MG were first evaluated in mouse models with αvβ6 expressing BxPC3 pancreatic cancer xenografts (Fig. 1d, Supplementary Fig. 4, and Table 3). This evidence concerns the gene MGAM and pancreatic neoplasm.