IRF2 and psoriasis: Furthermore, we detected an equally strong association when comparing differential expression between LSCP-HKs CT and LSCP-HKs IRF2 KD with genes expressed in psoriatic skin, suggesting that many psoriasis-related genes were upregulated by serial passaging and reversed by IRF2 KD to low passage-HSCP-HK levels (Supplementary Fig. 13).