CASP4 and infection: Other components of the NLRP3 inflammasome including Caspase 4/11, Gasdermin‐D, Caspase 1, and ASC were unchanged following infection in C3H/HeN (0.55, 0.13, 0.10, and −0.63 Log2 FC, respectively) and C57BL/6 mice (0.28, −0.17, −0.15, and −0.29 Log2 FC, respectively), apart from ASC which decreased in C3H/HeN (Figure 7a,b).