According to the revised WHO classification of tumors of the CNS 2016, the tumor classifies as desmoplastic/nodular, SHH-activated, TP53 wild-type MB (WHO grade IV).30 At age 16 years, the patient developed her first basal-cell carcinoma (BCC) and has subsequently gone on to develop 10 more BCCs, all within the radiation field and all amenable to surgical removal. This evidence concerns the gene TP53 and basal cell carcinoma.