Of note, patient SJMB054 had a somatic chromosome 6 monosomy, an alteration associated with MBWNT; however, a somatic CTNNB1 mutation was not detected and the brain tumor methylation classifier score was highest for MBSHH (MBSHH:0.9897 v MBWNT:0.0003). This evidence concerns the gene CTNNB1 and brain neoplasm.