PIK3CA and cancer: This observation was recently reported in SDC by Dalin et al30 and previously in other cancer types.31 In contrast to Dalin et al,30 who found co‐occurring PIK3CA mutations in all of their cases with HRAS p.G13R (n = 3) but none of their cases with HRAS p.Q61R (n = 4), all 5 of our PIK3CA/HRAS co‐mutated cases harbored the HRAS p.Q61R mutation.