To explore the possible functional relationship of c‐FOS with different allelic variants of ECR1 we carried out a cotransfection analysis in a human neuroblastoma cell line (SH‐SY5Y cells) with luciferase reporters containing the C‐allele and T‐allele of ECR1 in combination with an expression vector expressing the c‐FOS protein (pcDNA‐FosWT). The gene discussed is FOS; the disease is neuroblastoma.