TGF‐β directly inhibits the function of anti‐tumor effector cells (NK, CD8+ T cells, and γδ T cells) by downregulating the activating receptor NKG2D and generating and recruiting regulatory T cells and γδ T cells 4, 112, 143, 144, 145, 146, 147, 148, 149, 150. Here, TGFB1 is linked to neoplasm.