Deng et al. reported the tumor suppressive role of IQGAP2 which suppresses the ovarian cancer progression via suppressing Epithelial-mesenchymal transition by regulating Wnt/β signaling, thereby providing a potential biomarker and therapeutic strategy to combat ovarian cancer diagnosis (Deng et al., 2016). The gene discussed is IQGAP2; the disease is ovarian carcinoma.