SFRP1 and ovarian benign neoplasm: Using 7- genes panel [secreted frizzled receptor proteins 1, 2 4, 5 (SFRP1, 2, 4, 5), SRY box1 (SOX1), paired box gene 1(PAX1), and LIM homeobox transcription factor 1, alpha (LMX1A)], Sui et al. investigated methylation in 126 primary ovarian tumors, 75 benign ovarian tumors and 14 borderline ovarian tumors and in 26 OC serum samples.