TP53 and Alzheimer disease: As expected, because of the presence of an emerging body of scientific literature, we found that TP53, PIN1, and APP genes were top-ranked by text-mining via Beegle (Supplementary Table S1), confirming them as important players in the inverse association between cancer and AD (Shafi, 2016; Feng et al., 2017; Galvão et al., 2019).